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Nuclear Hormone (Steroid) Receptors as Drug Targets
Source pharma-CAL-ogy
Versions Available Windows
Summary
The program deals with:
  • the location of hormone receptors within the cell taking both glucocorticoids and oestrogens as examples
  • the biological effects of oestrogens
  • the speed of response following receptor activation
  • the detailed structure of the receptors and how interaction takes place with the ligand including tthe involvement of HSP90 and the "zinc fingers"
  • the nature of drug receptor binding
  • facilitation of gene transcription
  • the uses of the agonists and antagonists at the oetrogen receptor.
System Requirements

The package is supplied on a CD-ROM Installation Disc and can be installed to a local hard disc or network drive.