This program aims to teach the basic principles of
chemical transmission at synapses in the CNS and is intended for
first-level undergraduates. On completion of this package students
should be able to:
- descibe those neuronal structures of importance in synaptic transmission
- explain the steps involved in the transmission process
- list and categorise some of the major neurotransmitter chemicals
- describe the action of neurotransmitters at postsynaptic receptors
- explain the generation and interaction of EPSPs and IPSPs.
The program assumes knowledge of the mechanism of transmission
at the neuromuscular junction and would be expected to occupy students
for 2-3 hours. It is divided into several sections accessed from
the main menu:
Introduction; Neuronal Structure (structure of the neurone, sites
of excitation, neurotransmitter chemicals and their chemical characterisation,
basis of resting and action potentials);
Synaptic Transmission (the transmission process, synthesis, storage,
release, termination of effects);
Neurotransmitters and Postsynaptic Receptors (ligand-gated ion channels
and G-protein coupled receptors);
Neurotransmitters and Neuronal Excitability (generation and properties
of EPSP:s and IPSPs and their interaction to determine excitability).
The program contains a HELP facility and a bibliography for students.
|