| Contents |
| 1: Introduction to Mass Spectrometry |
| The student looks at how the mass spectrometer
works and then looks at the technique of mass spectrometry and how
this technique can be used in pharmaceutical/chemical analysis. |
| 2: Interpreting Mass Spectra |
| The student looks at the basics of interpreting
mass spectra, including how to interpret isotope patterns, fragmentation
patterns and metastable peaks. |
| 3: Fragmentation Patterns |
| The aims of this section are that the student
understands how various organic compounds fragment during mass spectrometry.
On completion, the student should be able to describe the fragmentation
patterns of ketones, esters, ethers and amides, the McLafferty rearrangement,
and the fragmentation patterns of peptides. |