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Using Chromatographic Data to Calculate Drug Content in Formulations v2.0
Source PCCAL, University of Strathclyde
ISBN: 1 84211 032 2
Versions Available Internet
Programmer Frances Penny
Subject Specialist Dr D.G.Watson
Summary
[Screenshot]
Screen shot from the package

This package focuses on calculation of the content of active ingredients in formulations using chromatographic data

The package allows the user to:

  1. Develop the ability to interpret British/European Pharmacopoeial Assays
  2. Accurately interpret chromatographic data and sample manipulations in order to calculate drug content in formulations.

On completion of this package, the student will be able to:

  1. Carry out calculations from chromatographic data by the internal standard method.
  2. Carry out calculations from chromatographic data by the external standard method.
Contents
Determinations by HPLC Using Internal Standards
  • Introduction to Method: Determination of Dexamethasone in Tablets
  • Example 2: Determination of Betamethasone in Tablets
  • Example 3: Determination of Prednisone in Tablets
  • Example 4: Determination of Betamethasone Valerate in Cream
  • Example 5: Determination of Triamcinoline in Tablets
Determinations by HPLC Using External Standard
  • Introduction to Method: Determination of Paracetamol in Oral Solution
  • Example 2: Determination of Cefuroxime in Injection
  • Example 3: Determination of Sodium Fusidate in Ointment
Determinations by GC Using Internal Standard
  • Introduction to Method: Determination of Miconazole in a Cream
  • Example 2: Determination of Hyoscine Hydrobromide in Tablets
  • Example 3: Determination of Chlorpheniramine Maleate in Oral Solution