The package introduces the concept together with practicalities such as what a QSAR can and cannot be used for and how one is generated using multiple linear regression techniques.

The package then goes on to cover the theoretical basis behind several substituent constants, that is :-

1. The Hammett electronic substituent constant (s).
2. Variants on the Hammett electronic substituent constant (s-,s+ and s*).
3. The Taft steric substituent constant (Es).
4. The Hansch / Fujita hydrophobicity substituent constant (p).

The aim of the package is not to teach students all there is to know about QSARs but rather to give them a gentle introduction to the basic concepts behind the subject, in particular the mathematics which they tend to find difficult.