Authors Acknowledgement 1. Abstract 2. Introduction 3. Study design 3.1 Aims 3.2 Multi-site Evaluation Study 3.3 Evaluation for Consortia 3.4 Classroom Studies 4. Methods 4.1 Evaluation Strategy 4.2 Summary of Methods 4.3 Limitations 5. Nomenclature of Organic Compounds 5.1 Design and Structure of the Package 5.2 Methodological Issues 5.3 Results 5.3.1 Computer Confidence 5.3.2 Help Required 5.3.3 Subject Confidence 5.3.4 Learning Outcomes 5.3.5 Learning Strategies 5.4 Conclusions on Nomenclature of Organic Compounds 6. Simulations of Pharmacological Experiments on the Isolated Guinea Pig Ileum 6.1 Design andStructure of the Package 6.2 Study Groups 6.3 Teaching and Learning Case Studies 6.3.1 Timetabled class and Practical- University of Wales, Cardiff 6.3.2 Structured Exercise in a Time-tabled Class- University of Bath 6.3.3 Practical and CAL Sessions Working in Groups -Liverpool, John Moores University 6.3.4 Extended Study on a Casual Basis- University of Brighton 6.4 Student Opinions on the Guinea Pig Ileum Package 6.5 Conclusions on the Guinea Pig Ileum Package 7. Problem Solving in Community Practice 7.1 Design and Structure of the Package 7.2 Study Groups 7.3 Teaching and Learning Case Studies 7.3.1 Timetabled Class without Tutor Support- University of Bath 7.3.2 Timetabled Class without Tutor Support- University of Wales, Cardiff 7.3.3 Extended Study on a Casual Basis- University of Brighton 7.4 Student Opinions on the Problem Solving Package 7.5 Conclusions on the Problem Solving Package 8. Overall Conclusions 8.1 Strategy and Methods 8.2 Package Design and Content 8.3 Learning Outcomes 8.4 Learning Strategies 8.5 Future Work 9.References Appendix A - Examples of Evaluation Measures Appendix B - Transcript of Open Ended Questionnaire Responses B1 Nomenclature of Organic Compounds B1.1 Bath B1.2 Brighton B1.3 Liverpool B1.4 Manchester B2 Experiments on Isolated Guinea Pig Ileum B2.1 Bath B2.2 Brighton B2.3 Cardiff B2.4 Liverpool B3 Problem solving in Community Practice B3.1 Bath B3.2 Brighton B3.3 Cardiff