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9b. Appendix B - Transcript of Open Ended Questionnaire Responses

B2. Experiments on Isolated Guinea Pig Ileum

B2.4 Liverpool

STUDENT ID

WHAT DO YOU THINK YOU WERE MEANT TO LEARN FROM THE PACKAGE?

FROM THE SECTIONS YOU STUDIED, WHAT, IF ANYTHING, DID YOU FIND EASY TO GRASP?

FROM THE SECTIONS YOU STUDIED, WHAT, IF ANYTHING, DID YOU FIND DIFFICULT TO GRASP?

ANY FURTHER COMMENTS OR OBSERVATIONS

40191

Information of different topics concerning agonists.

I found some of the theory and experiment easier to understand.

-

About an hour.

40281

The basic concepts of drug action on receptors.

I think the sections I did were not difficult to grasp.

-

About 2 hours.

40583

Response to drugs.

-

-

2 hours.

40683

It has more advantage for self studying rather than reading books. It is good illustration.-

-

-

I have been working for two hours. It was helpful and easy to receive information. Good illustration.

40791

To understand the set-up and theory behind the Guinea Pig Ileum experiment.

Definitions - for example of agonists and antagonists. Also the experimental set-up.

Some of the calculations relating to finding out concentration.

1 ½ hours.

40891

-

Nothing

Answering the questions at the end,

I spent approximately 2 hours on the package. The package is a good way of revising and learning as all the information is there.

40991

Background knowledge for the work covering the module for this semester.

Nothing was easy but labelling the tissues was not that difficult a lot of guessing was involved.

Most of the package.

1 ½ hours spent working with package. Didn't find it useful at all would have rather had a lecture/tutorial covering the subject. However if print outs could be obtained from the computer this would be helpful.

41091

The Theory of Agonists, Antagonists and expt set up of Guinea Pig Ileum.

Dose-Response Curves of agonists.

Comparing dose-response curves.

I spent two hours on this package. The package is easy to understand, and going through questions in the package made me understand the subject material more thoroughly.

41191

The effect of agonists on tissues. How and why they work.

The overall idea that agonists effect tissues etc.

Dose response curves - higher and lower affinities.

Approximately 1 ½ hours.

41293

About the Agonists and Antagonist receptors, factors affecting their function.

Definitions, curves.

Nothing.

An hour and half. 90 mins approx. The package have a lot of repeated information and I reached a point, that it was boring.

41382

How agonist and antagonist effect receptors and how to demonstrate this experimentally.

The idea of agonists and antagonists.

The graphs of dose and response.

1h ½

41491

Learn how to use the package, and to understand the theory of agonists.

-

-

About 2 hours.

41583

Easily to understand the subject.

No.

The interrelationship between the drugs and body.

1 hour and half. The package very good to me because it give a good information for the subject I learn.

41691

An understanding to how an agonist works and how this applies to the guinea pig ileum.

Theory of Agonists.

-

4 hours.

41791

Everything, as I hadn't studied agonists before.

-

The graphs.

2 ½ hours.

41891

Information involving actual experimental set-up and some theory behind it also.

The set-up of the apparatus and some of the Biology involved.

Bits relating to receptors, agonists and the calculations.

1 ½ hours.

41982

-

-

-

1 ½ hours.

42091

Basic information about agonists and antagonists.

The difference between an agonist and an antagonist.

I can't remember.

1 ½ hours.

42191

What an agonist is, how an agonist works and it's effects on the Guinea Pig Ileum

What an agonist is and how it works. (the theory of agonists).

The experimental set-up.

2 hours.

42281

General theory and background information on agonists and their effect on the Pig Ileum as an example.

Constructing the Dose Response Curves and the theory behind agonists.

Found the section about receptors difficult to grasp.

2 ½ hours. I found the computer package a very clear and effective way of learning a topic.

42391

The difference between agonists and antagonists and the effect they have on various receptors, also how to use this information experimentally using live tissue.

How to set up the equipment for the experiment, and what the main aims of the experiment were.

-

3 hours.

42481

General knowledge involving Agonist drugs and their effects.

Dose response curves.

Nothing.

1 hr 30 mins

42591

Basic principles of effect of agonists on the guinea pig ileum

The experimental set up.

Bath conc

1 ½ hours

42691

To get an introduction to new terms that we will be associating with in this module (SBT)

I found it hard, as it was all new material, but it showed us a lot about drawing graphs and recording results.

An understanding of the programme.

2-3 hours, I found it helpful to reinforce my confidence and it provide us with good information and during this year, I'll probable make use of this programme.

42792

The effect of drugs upon tissue.

-

-

3 hours.

42882

The effect of agonists on guinea pig ileum

Agonists make the ileum contract

-

2 hours.

42983

Theory of agonist and some applications on it.

Agonist.

Stuff like intramural plexus.

One and half hour.

43093

How agonists act on the Guinea Pig Ileum and the different receptors.

Different colors of text which enabled me to grasp the main points easily.

The clock-like cycle demonstrating how to divide your time when doing the experiment.

~ 2 hours.

43192

It was to reinforce and further explain the theory of drug response given in lectures.

It demonstrated well the differences in graphs for effectiveness and efficacy.

The calculations regarding KA etc.

1 ½ - 2 hours. I thought that this package was very good and necessary, however going through it in a group of people was very detrimental to how much was learnt.

43381

Obtain a more visual representation of the project and give help understand practical work.

Drawing up the curves.

The work on autonomic ganglion.

About 2 hrs. It is good source for revision, when you want to quickly go through the package.

43481

The action of agonists, of different types, upon smooth muscle.

Definitions of relevant terms.

The intricacies of the subject.

1 hour 20 minutes.

43591

About agonists and their effects of smooth muscle.

The dose response curves.

The calculations and equations association with occupancy made no sense what so ever.

About 2 ½ hours.

43681

Both the theory and practical side of how the guinea pig ileum reacted towards different substances.

Information was given step by step, experimental side worked together with theory to explain concepts, making it easier to understand.

Too much information to take in relatively quickly.

1 ½ hr.

49781

Information about agonists.

Constructing dose response curves.

-

1 ½ hrs - useful package - helped a great deal. Slightly tedious reading papers and pages of theory. Question and answer sections useful.

43881

The effect of Agonists on guinea pig ileum and how to plot and interpret dose response curves.

Dose response curves.

Theory of Agonists.

2 hours; 2 hours, I must admit, was long enough for me, if not a little too long. However, the package, I'm sure, was of benefit.

43993

To know how to use the computer more and to know some information and some facts about it.

The affinity, efficacy, agonist and antagonist definitions the curves were easy.

Some of the diagrams.

1 hour and half an hour.

44091

How Agonist work.

The Dose Response Curve.

-

2 ½ hours.

44193

All the effects of both agonists and antagonists on the guinea pig ileum.

Everything.

None.

1 ½ hours. Even though the information on the package is easy to grasp, it is not easy to remember them.

44291

Effect of agonists on guinea pig ileum.

Experiment procedure. Setting up of the apparatus.

The theory was complex.

1 hour 40 mins, spent on the package.

44391

Basic understanding of the experiment and guinea pig ileum.

-

There was too much information to grasp.

1 hour.

44481

About Agonists/Antagonist/Ach etc

Ileum set up - As it was diagrammatic.

The KA section. Too much to read though (Approx 24-30 Pages)

2 hrs max!

44591

Learn about agonist/friction/response, receptor sites etc. via pharmacological experiments.

Most of the package I used was O.K. to grasp.

Molar calculations.

1 ½ hrs.

44691

Learn about agonists and the theory behind them.

The dose/response curves.

The calculations associated with occupancy.

I've worked on this package for about 2 hours.

44891

How agonists work.

The overall structure of the programme.

-

2.5 hrs.

44991

How to set up guinea pig ileum experiment. What should happen and why it happens.

Agonist theory.

None, but there was lots to remember.

1 ½ hours.

45093

Agonists, antagonists, efficacy, affinity, occupancy, receptors, Guinea Pig Ileum experiment.

No particularly easy section.

No particularly difficult one too.

1 ½ hours. It is not effective to go through the whole package in one period of time. Learning would be more effective if the package is learned in several blocks of time depending on individual learning habit and efficiency.

45181

How to set up the experiment construction and comparison of dose response curve. The effects of agonists.

Setting up of the experiment.

Construction of Dose Response Curves.

1 hour 30 mins.

45381

-

The way it was set out.

-

1 hr.

45481

-

-

-

1.5 hours.

45581

All about agonists etc.

The Set up part.

The explanations of Ka etc

I spent about 2-3 hours working on the package but for me, at the end of session I became tired looking at the t.v. screen!

45781

About how agonists work and how different drugs affect how they work.

How to set the experiment up and what to do.

How to compare dosage-response curves.

2 hrs.

45883

-

-

-

-

45983

To understand the procedure before the experiment is done.

Not really.

The section of calculation.

Two hours. After going through the package, I think, now I get more confident.

46091

About drug receptors, agonists, partial agonists and antagonists. Plus how to set up the experiment.

Moving through the package, how agonists work.

The experimental set-up.

About 2 hours. Need to spend more time than 1 lesson on the package because it is a lot of info to absorb all at once!

46183

How to set up experimental set up then to construct close-response curve.

Everything.

Nothing.

Two hrs.

46282

Agonists and Receptors and practical set up of guinea pig ileum.

Diagram of contracting ileum was good.

-

Approx. 1 ¼ hours. Would like to go through it at my own pace - take notes etc. Hard to stare at screen for more than 2 hours at a stretch.

46391

How agonists work on muscle, how to set up experiment to find out.

Experimental set up.

Calculation.

Spent about 2 hours working with the package found it quite helpful but took a long time to work through.

46493

Agonists what they are and their effects on the human body.

The experiment as the drawings were clear and demonstrations, very good.

Effect of agonist on guinea pig ileum.

Approximately 2 hour.

46581

To develop an understanding of drugs and there effects on the body.

-

Dose response curves, Efficiency

2 hrs.

46693

Action of drugs on receptors, and how the response varies with the dose.

Everything.

Nothing.

About 2 hours. The package is good. I can learn a lot from it. Its only that this time I didn't want to memorise or grasp everything; I was only evaluating.

46791

Details about the set up of the experiment and expected outcomes.

Experimental set up. Constructing and comparing dose/response curves.

-.

2 ½ hrs.

46893

Practical set up and effects of agonists and receptors.

I don't know.

The set up of the apparatus.

2 ½ hrs. It was confusing.

46981

Yes.

Constructing dose response curves.

 

2 hours.

47081

Theory of the guinea pig ileum.

Constructing dose response curves.

Agonists theory.

About 1 ½ hours.

47191

Information to help understanding the practicals.

Experimental set up.

Agonists on guinea pig ileum.

2 hours.

47283

Excellent… it very simple to follow and a very good program indeed.

The drawing and the appropriate name associated to it.

No-one.

Two hours.

47381

What it was teaching.

Receptors.

N/A

2 hrs.

47791

How to set up the experiment and background information relating to the experiment directly.

Theory and labelling parts.

Dose curves.

2 ½ hours. Parts of the package were slightly confusing.

47882

The theory behind the experiments.

All of it.

Nothing.

2 ½ hours.

47981

The actions of Agonists on t he GPI and how to compare the results and interpret them.

I found that comparing the dose response curves was not too difficult.

The construction of the d-R curves.

I spent approx 120 mins with the package. I personally find it much more difficult to learn from the computer than from lecture notes and handouts.

48091

Details about the set-up of the experiment, and expected outcomes.

The experimental set-up. Comparing and constructing dose response curves.

The theory.

2 ½ hours.

48185

-

No.

Yes.

-

48391

About how agonist affect drug receptors.

Analysis work.

Calculation.

1 ½ - 2 hours. There was too much to absorb.

48591

About agonists.

What the package required me to do and how to do it.

Calculations.

1 ½ hrs. I would have found this much more useful if I had already had the lectures. It seemed to be a good revision programme.

48683

-

Illustration.

-

About 1 - 2 hours. The questions especially calculations are quite easy - should be difficult and more than two.

48783

-

Diagrams and graphs.

None.

Spent around 6 hours.

48891

About the theory of agonists and their effects on different tissues.

I found the theory on the agonists quite easy to grasp and the Experimental set up.

Using the computer package to compare dose response curves - There were not enough explanations.

2 hours approximately was spent. More time would be required to understand package better.

48981

About agonists, contractions, how occupy receptors, calculations.

It was all fairly o.k.

-

1 ½ hrs.

49081

The general ideas to do with agonists.

Constructing dose response curves.

Theory.

2 hours.

49192

Put knowledge into practice and test myself on what I previously learned in the lectures.

Most things.

Diagram of guinea pig ileum.

1 hr 30 min.

49392

Overall picture of ANS and Dose responses.

I found it easy to answer the questions on the graphs.

Calculations.

2 hrs. Would have liked to have worked through the package a few times before and after the test. Overall. Most helpful and well set out.

49481

Agonists and how they interact within the Guinea Pig Ileum.

Comparing and constructing dose response curves.

-

2 ½ hours.

49581

Theory.

Experimental set up.

Agonists on guinea pig ileum.

2 hrs.

49783

Theory.

Experimental set up.

Agonist - theory.

About 1 ½ - 2 hrs.

49891

To relate required knowledge from lectures to the package content. To learn more about what was thought in the lectures.

The experimental set up, the effect of the acetylcholine on the Guinea pig ileum showing contraction and relaxation. The agonist response curve.

-

About two hours.

49991

A basic understanding of the effects of the various drugs on Guinea Pig Ileum and its structure.

The graphs relating to affinity and efficacy.

The rate equations and also the calculations concerning concentration.

2 hours.

50591

About receptors, Agonists how the guinea pig ileum reacts to a drug.

The way that you got motion pictures with key words lit up which you could click on to get further explanation.

How if you got the answer wrong sometimes it wouldn't show you how to work it out.

2 hours. Would need to work through package again to become clearer on subject.

50691

Appliance of experimental data to graphical representation in relation to drug responses.

The graphical representation of the data recorded.

The high level of information given in the package.

2 ½ hrs.

50791

Theory and experimental factors of the above (Q1).

The experimental set up.

Receptors and agonists (theory)

1 ½ hours.

50891

About the action of agonists, particularly their effects on the guinea pig ileum.

The dose response curves.

The section dealing with the nervous system.

One session that last about 1 ½ hours.

50991

Basic theory.

Comparison of dose response curves/affinity.

Some of the Ka type calculations.

2 ½ hrs.

51091

The effects of Agonists on Guinea Pig Ileum.

Agonists - Constructing Dose - Response Curves.

Receptors.

Approx. 2 hours.

51181

The major topic was dose response curves.

The method of agonists, attachment to receptors.

Bath concentrations.

2 hours.

51291

To understand the practicals in more depth, To be able to construct graphs and set up experiments. To understand the theory behind it.

The efficacy and affinity graphs and the experimental set up.

The equation for KA and the theory behind it.

2 hours.

51383

To understand and remember it.

The whole package is basically easy to grasp.

-

Two hours. It is very good.

51483

Understand the theory of the agonist, receptors and antagonist.

Yes.

No.

3 hours.